胡家新

::个人资料::

   名:  胡家新

   别:

最高学位:  博士

   称:  中级(主治医师)

   务:  

E-mail     hjxlmy@outlook.com

   话:  18805152985

研究方向: 1.动脉粥样硬化及动脉瘤发病机制极其相关药物的筛选 2.靶向递送SeMet治疗心血管疾病新型材料的开发与应用 

::个人简介:::

胡家新,博士/研究生,主治医师,硕士生导师,毕业于南京大学。现为硒资源研究与生物应用湖北省重点实验室PI

2019. 09-2022. 06:南京大学医学院,临床医学专业研究生,获临床医学博士学位(师从著名心脏病专家徐标教授);

2016. 09-2019. 06:南京大学医学院,临床医学专业研究生,获临床医学硕士学位(师从著名心脏病专家徐标教授);

2010. 09-2015. 07:湖北民族大学医学部,临床医学专业本科生,获临床医学学士学位。

::承担的科学研究和教学研究项目::

1、湖北省自然科学基金青年项目(基金号:2023AFB127):糖尿病背景下PKM2表达下调致VSM代谢重编程经Glycine-GARS-GlytRNA抑制腹主动脉瘤形成的机制研究(项目名称)2023. 07-2025.6主持人,在研。

2、湖北硒与人体健康研究院开放课题(基金号:2023XDSYS05):含有硒代蛋氨酸的可黏附型心肌贴片对心肌梗死后心脏重构的影响及其机制研究(项目名称)2023. 08-2024.7主持人,在研。

::科研教学成果奖励:::

12021年博士研究生国家奖学金

::公开发表论文、教材及专著::

1Jiaxin Hua #, Yuyu Lia #, Zhonghai Weia #, Haiting Chena, Xuan Suna, Qing Zhoub, Qi Zhang a, Yong Yina, Meng Guoa, Jianzhou Chena, Guangyao Zhaic, Biao Xua *, Jun Xiea * A Reduction in the Vascular Smooth Muscle Cell Focal Adhesion Component Syndecan-4 is Associated with Abdominal Aortic Aneurysm FormationClinical and Translational Medicine中科院1IF=11.492

2Jiaxin Hu† , Ying Zhang† , Liaoping Hu† , Haiting Chen† , Han Wu, Jianzhou Chen, Jun Xie, Biao Xu* and Zhonghai Wei*A reduction of Syndecan-4 in macrophages promotes atherosclerosis by aggravating the proinfammatory capacity of macrophages;Journal of Translational Medicine(中科院2IF=8.44)

3Jinxuan Zhaoa #; Xueling Lib #; Jiaxin Hua #; Fu Chena; Shuaihua Qiaoa; Xuan Suna; Ling Gaoa; Jun Xiea *; Biao Xua *Mesenchymal Stromal Cell-Derived Exosomes Attenuate Myocardial Ischemia-Reperfusion Injury through miR-182-Regulated Macrophage PolarizationCardiovascular Research(中科院1IF=14.239)

4.Jiaxin Hua #, Song Shena #, Jiamin Xua #, Wengfeng Zhangb, Haiting Chena, Xuan Suna, Yu Qia, Ying Zhanga,Yuyu Lia, Qi Zhang a, Meng Guoa, Ningxin Pengb,Biao Xua *; Trimethylamine N-oxide promotes abdominal aortic aneurysm formation by enhancing the aortic smooth muscle cells senescence in miceJournal of Cardiovascular Translational Research(中科院2IF=4.132)

5Jiaxin Hu1,2Jiamin Xu2Xi Tan3 Dong Li4Dejiang Yao5Biao Xu3Yuhua Lei1Dapaglifozin protects against dilated cardiomyopathy progression by targeting NLRP3 infammasome activationNaunyn-Schmiedeberg's Archives of Pharmacology(中科院4区,IF=3.6)

6Yafei Shia,b,1 , Jiaxin Huc,1 , Jin Gengb,1 , Tingting Hub , Bingjian Wangb , Wenting Yanb , Yicheng Jiangb , Jiangjin Lib , Shaowen Liua,⁎; Berberine treatment reduces atherosclerosis by mediating gut microbiota in apoE-/- miceBiomedicine & Pharmacotherapy中科院2区,IF=7.419

 

::课程建设::